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Scientific Articles - ADHD

Drug Abuse and DependenceADHDBinge-Eating DisorderPsychiatric and Neurological DisordersObesity and Metabolic Disorders

Pillidge K, Heal DJ, Stanford SC. The NK1R-/- mouse phenotype suggests that small body size, with a sex- and diet-dependent excess in body mass and fat, are physical biomarkers for a human endophenotype with vulnerability to attention deficit hyperactivity disorder. J Psychopharmacol, 2016; 30: 848-55.

Bolea-Alamañac B, Nutt DJ, Adamou M, Asherson P, Bazire S, Coghill D, Heal D, Müller U, Nash J, Santosh P, Sayal K, Sonuga-Barke E, Young SJ; British Association for Psychopharmacology. Evidence-based guidelines for the pharmacological management of attention deficit hyperactivity disorder: update on recommendations from the British Association for Psychopharmacology. J Psychopharmacol, 2014; 28: 179-203.

Pillidge K, Porter AJ, Vasili T, Heal DJ, Stanford SC. Atomoxetine reduces hyperactive/impulsive behaviours in neurokinin-1 receptor 'knockout' mice. Pharmacol Biochem Behav, 2014; 127: 56-61.

Pillidge K, Porter AJ, Dudley JA, Tsai YC, Heal DJ, Stanford SC. The behavioural response of mice lacking NK₁ receptors to guanfacine resembles its clinical profile in treatment of ADHD. Br J Pharmacol, 2014; 171: 4785-96.

Ash ES, Heal DJ, Clare Stanford S. Contrasting changes in extracellular dopamine and glutamate along the rostro-caudal axis of the anterior cingulate cortex of the rat following an acute d-amphetamine or dopamine challenge. Neuropharmacol, 2014; 87: 180-7.

Rowley HL, Kulkarni RS, Gosden J, Brammer RJ, Hackett D, Heal DJ. Differences in the neurochemical and behavioural profiles of lisdexamfetamine methylphenidate and modafinil revealed by simultaneous dual-probe microdialysis and locomotor activity measurements in freely-moving rats. J Psychopharmacol, 2014; 28: 254-69.

Heal DJ, Smith SL, Findling RL. ADHD: current and future therapeutics. Curr Top Behav Neurosci, 2012; 9: 361-390.

Heal DJ, Cheetham SC, Smith SL. The neuropharmacology of ADHD drugs in vivo: insights on efficacy and safety. Neuropharmacol, 2009; 57: 608-618.

Heal DJ, Smith SL, Kulkarni RS, Rowley HL. New perspectives from microdialysis studies in freely-moving, spontaneously hypertensive rats on the pharmacology of drugs for the treatment of ADHD. Pharmacol Biochem Behav, 2008; 90: 184-197.

Heal DJ, Pierce DM. Methylphenidate and its isomers: their role in the treatment of attention-deficit hyperactivity disorder using a transdermal delivery system. CNS Drugs, 2006; 20: 713-38.

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